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Hypoglycaemia can occur, particularly when GLP-1 agonists are used in combination with insulin or sulphonylureas, though the risk is lower when used as monotherapy due to their glucose-dependent mechanism

Interactive diagrams visualizing signaling pathways and receptor interactions

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[1] The authors framed the observed metabolic shifts as a direct effect on lipid handling in the model rather than appetite suppression

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It targeted exactly where the health risk concentrates